22,334 research outputs found

    The effects of dog management on Echinococcus spp. prevalence in villages on the eastern Tibetan Plateau, China

    Get PDF
    Background The pastoral area of the eastern Tibetan plateau is a very important human echinococcosis endemic region. Domestic dogs are the main definitive host for the transmission of Echinococcus granulosus sensu lato (s.1.) and E. multilocularis to humans. To control the infection risks, a national-level canine echinococcosis prevention and control program has been implemented since 2015 in Shiqu County, Sichuan, China, The objective of this investigation was to evaluate its effect on Echinococcus spp. prevalence in dogs. Methods We surveyed 69 households with 84 owned dogs, for dog keeping information in the villages of Rizha and Eduoma. A total of 105 dog fecal samples, consisting of 75 from owned dogs and 30 unknown dog fecal samples were collected between 2015 and 2017 to determine Echinococcus spp. prevalence using copro-PCR. Eight variables based on household surveys were included into a logistic regression model for significantly relevant factors to canine echinococcosis prevalence in dogs. Results The overall Echinococcus spp. copro-DNA prevalence decreased significantly in dogs from 51.2% (2015) to 20.0% (2017) in Rizha, and insignificantly from 11.5% (2016) to 4.3% (2017) in Eduoma. Echinococcus multilocularis was the most prevalent species continually detected during the entire research period, while E. granulosus was rare and not detected in 2017. Echinococcus shiquicus prevalence was as high as E. multilocularis , although only detected in 2015 in Rizha. Unleashed dog feces were mainly collected in Rizha Village in 2015. Although 93.2% of owned dogs were leashed, and the monthly praziquantel dosing rate reached 97%, E. multilocularis infection could still be detected in 11.1% of owned dogs in 2017. Monthly deworming, leashing dogs 24h per day, and the avoidance of dogs feeding on livestock viscera are significant measures to prevent canine echinococcosis infection in owned dogs. Conclusion Carrying out a canine echinococcosis prevention and control program can significantly decrease the Echinococcus prevalence. The potential contact between leashed dogs and wild small mammals is still a risk to re-infect owned dogs. This study shows that the long term application of regular dog dosing in the vast remote echinococcosis endemic areas of west China is still challenging

    The Maximum-Weight Stable Matching Problem: Duality and Efficiency

    Get PDF
    Given a preference system (G,≺) and an integral weight function defined on the edge set of G (not necessarily bipartite), the maximum-weight stable matching problem is to find a stable matching of (G,≺) with maximum total weight. In this paper we study this NP-hard problem using linear programming and polyhedral approaches. We show that the Rothblum system for defining the fractional stable matching polytope of (G,≺) is totally dual integral if and only if this polytope is integral if and only if (G,≺) has a bipartite representation. We also present a combinatorial polynomial-time algorithm for the maximum-weight stable matching problem and its dual on any preference system with a bipartite representation. Our results generalize Király and Pap's theorem on the maximum-weight stable-marriage problem and rely heavily on their work. © 2012 Society for Industrial and Applied Mathematics.published_or_final_versio
    • …
    corecore